WHO ‘S AFRAID OF BIOTERRORISM ?

 

or

 

WHO’S AFRAID OF THE BIG, BAD BUG?

 

 

 

WEBQUEST FOR 11TH Grade Biology / Research / Language Arts

 

Designed by

 

Helen Kellert

 

 

VIEW THE ACCOMPANYING POWER POINT PRESENTATION ON BIOTERRORISM FOR A QUICK OVERVIEW OF THIS  PROJECT !!!!!!!!!

 

 

INTRODUCTION

The Board of Education in your town has a social problem. It is concerned that local schoolchildren  may have misconceptions about the nature of and realistic measures to be taken against bioterrorism.

 

 To help solve this problem, and to correct the lack of a school  bioterrorist policy, The Board needs students of your age to reach out and communicate to other students in your own and in other schools.  The Board is asking you to help establish a set of protocols, guidelines  and fictional or journalistic materials.These will be used to make students aware of the nature of bioterrorism warfare, of the ways pathogens and microbes are created, cultured and used and what schools should be doing to handle a future bioterrorism attack. 

 

 

TASK and PROCESS

You and your team of four other students have been called in by the Board to help with this problem.   You will be researching existing evidence of bioterrorism, determining bioterrorism ’s causes and investigating existing and possible policies in New York City schools. 

 

You will be

a)      educating children in schools about biological agents

b)      alerting students  to the real dangers posed by biological attacks

c)      guiding students on how to read, sift through and evaluate  the conflicting or ambiguous reports and journalism on the topic

d)      recommending measures that schools could adopt to prevent both  bioterrorism and panic.

e)      informing students of  realistic  preventative and medical steps to be taken

f)        helping children distinguish between  reasonable caution and irrational fears in their responses to biological threats

g)  creating a fictional or dramatic work  (see below  * )

 

OR

 

 writing a recommendation for schools on how to make the school environment safe (see below**)

 

* Your  creative product  to be distributed to or performed for children must highlight information about and responses to all aspects of biological threat. As a model of a writer using science to write a work of fiction, the Board needs you to read The Andromeda Strain by Michael Chrichton and to advise it on how to use or adapt this in the schools. To explore this novel, your team must answer any TWENTY questions from The Andromeda Strain  list  following this section.

 

Your creative product can be in the form of written pamphlets, newsletters, letters to schoolchildren, skits, scenarios, plays, dialogues, interviews, pages from a novel, a fairy tale, short stories, movie screenplays, comedy routines, songs, a legal brief, courtroom scene, debate etc.  You may use one or several of these suggestions or supply your own. As Michael Crichton wrote his novel based on a scientific possibility, so will your creative work use the research you gather in exploring a) through f) above. Your group creative work must be FIVE typewritten pages. 

 

 There are two other requirements here.

The first  is that the work must speak directly or indirectly to realistic responses as opposed to exaggerated, inappropriate responses to biological threats.  You are writing Science Fiction, not Science Fantasy. The fictional characters or situations you describe or evoke must  be based on the research you do on websites, newspapers, books etc. Your work should allow your student viewers or readers to arrive at their own conclusions about appropriate reactions.  Remember, satire and laughter are great ways to highlight ridiculous or incorrect or crazy behavior!

The second is that at least TWENTY facts or pieces of information from your research must make an appearance in your creative work. Highlight and number these in your work.

 

 

** If  your group decides to  to write a five  - page { typed, DOUBLE  - SPACED} proposal, you are required to supply recommendations and guidelines for individual schools to adopt in order to handle educational, medical and  law enforcement measures issues necessary.  Your proposal should analyze how a school should interface with hospitals, world medical experts, the National Institute of Health (NIH ), pharmaceutical companies,  national and international law enforcement agencies, from local police Precincts to  the FBI. .   Use The Andromeda Strain to focus on measures to safeguard the correct handling of dangerous biochemical organisms.  You may choose to study all the mistakes that occurred in the novel and describe in your work the various scientific and police precautions that a school would need to know about or enforce. 

At least TWENTY facts or pieces of information from your research must make an appearance in your proposal. Highlight and number these in your work.

 

 

Here ‘s the work !

 

1.     Read The Andromeda Strain .

2.      

As a group, decide which  twenty questions you wish to answer and which vocabulary words each member will look up.

 

Assign a date when all team members will bring in vocabulary definitions.

Assign a date by which team members bring in four different vocabulary quizzes for other team members.  Each member designs quizzes on his/her vocabulary words.

Assign a date when the group will have a Vocabulary Quiz Day. On that day, all members will take quizzes. Each member will take home his /her quizzes to grade at home.  Arrange to have one member keep all graded quizzes.

 

Divide the Andromeda Strain questions so that each member answers four questions.                                       

 

 

 

2. Find twenty websites (four per team member) from the long list below that will help you supply the answers to the topics in the EVALUATION, below. Divide work so that all team members share doing this research.

 

3.  Create a  work of fiction, fantasy, extract from a diary. T.V show etc. etc. 

                                                                       

                                                OR

     

Write a proposal as described above.

 

 

 

 

 

 

 

The Andromeda Strain:      Answer 20 Questions from the following.                                                                                                 

    

     The following words appear in this novel

 

You are required to look up and KNOW all vocabulary words listed on these handouts.

(*Reading the pages provided next to many of them just might provide all your definitions and explanations.)  WRITE a sentence for 25 new words

 (  25  Sentences Total for the group)

 

 

exogenous (p 80)

electrocardiogram(p99)

to cauterize (p 80)

electrocephalogram (p 100)

prophylactic (p 86)

a quonset hut (p89)

symptomatology (p86)

albumen (p 99)

pharmacology (p86)                            

systemic (p 100)

febrile and afebrile (p85)

innocuous (p 108)

deleterious (p 37)

prodigious (p 38)

velocity                 

vector

*exotoxin (p 113-4)                              

*coagulase (p 113-4)

*hemolysis (p 113-4)

*streptokinase (p 113-4)

assays (p 144)      

to succumb (p167)

cumbersome(ly) (p 147)                      

 

 

to discard (p167)

hypoglycemic (p 147)

coagulation          

 

 

requisition (p149)

pathological (p169)

agar (p 157)          

*anemic (p 171)

ubiquitous (p 161)                               

*prothrombin (p 172)

*heparin (p 167)  

thromboplatin (p 180)

doubletalk (provide also the example of doubletalk on p187)

*polymer (p 190)

rebuttal (p 195)

 

 

1) p35-36.  Crichton presents a scientific paper by one of his characters:

        a) Discuss the effectiveness of the title.

        b) Provide a summary of Merrick’s findings.

        c) Analyze the use of charts

                  d) Note the alternating sequences in the paper. Concise alternates with verbose, simple alternates with abstract, long  alternates with short sections.  What do you think of this use of opposing styles?

2) p 37.  Stone’s achievements.

Where could we go to verify, expand our background and knowledge of these bacteriological advancements? 

Describe in detail a) the internet source you would embark on for this; and b) your findings – (for this, use the summary in appendix I of the novel) 

3) p 57-61.  How effective is Crichton’s use of text (p57) and maps (p58-60) to describe and amplify the velocity and vector issues of flying into Piedmont?  Would text alone or maps alone have done the job?  - Explain.

4) Why does Crichton put responsibility of nuclear weapons to cauterize deadly exogenous organisms into political, not scientific, hands? (p 80-82)

5) Describe three other current issues in modern science and modern life where a political decisions has been or will have to be made based on scientific issues, facts, advancements, crises?

6) What are the implications or consequences of such decisions?  Explore each one.

7) How does the information on the bottom of p90 – top of p91 relate to your analysis of political and scientific decision-making?  Might your scenario have to include a bypassing of the political process?  - Explain.

8) In the Acknowledgements (p XI ):

        a) What is Crichton’s reason for telling a fictional story of a scientific crisis?

        b) How relevant do you think this is to life in America now?

9) Why does Crichton include in the opening “actual”(although fictional) pages and text of a file (p84) which he himself calls “bad”, unreadable, hard to understand due to bureaucratic jargon and references?

10) From your work on successful scientific writing, explain whether the information on p85-86 (the five stages of primary parameters) meets the criteria for clear, concise scientific writing.  Analyze 3 examples, 3 phrases, or 3 sentences of this writing, examining how each is or is not a sample of effective scientific writing.

11) In the file on the Odd Man Hypothesis (p87), how does Crichton’s trick of leaving out a page affect suspense and tension for the reader as well as provide twists and interests for the plot?  - Explain.

12) p 97-98.  What is the effect in the story of the recitation of the long list of dangerous bacterial organisms?

13) Evaluate Crichton’s use of graphs and pictorials on page 99.  Would it have been better or not to use written text?  - Explain.

14) p 130.  In the light of what you’ve learned about aspects of a scientific paper, analyze Crichton’s fictional Summary and Results of the Odd Man Hypothesis.  Are they complete and concise?  Explain.  Could this experiment be repeated?  - Why/Why not?

15) p 97-98.  What is the effect in the story of the recitation of the long list of dangerous bacterial organisms?

16) Evaluate Crichton’s use of graphs and pictorials on page 99.  Would it have been better or not to use written text?  - Explain.

17) p130.  In the light of what you’ve learned about aspects of a scientific paper, analyze Crichton’s fictional Summary and Results of the Odd Man Hypothesis.  Are they complete and concise?  Explain.  Could this experiment be repeated?  - Why/Why not?

18) How does the Analysis (p105 – paragraph beginning “The results......”) provide or not provide a thorough examination of the experiment, the implications of the experiment, and recommendations following the experiment?

19) p108.  In the middle of the novel, Crichton summarizes the book’s previous action and findings in one sentence: “They reviewed the findings of rapid deaths, the bizarre suicides, the clotted arteries, and the lack of bleeding.”  Is this sentence the equivalent of the material of an Abstract (the beginning of a scientific paper) or to the Results(the middle of a paper), or to the Discussions(the end of a paper)?  - Explain.

20) Crichton implies the posing of the scientific problem: ”How does the Scoop bacteria work to destroy human tissue and metabolism” by having his character Burton think about possible mechanisms of the phenomenon.  This is how scientists begin asking themselves questions they wish to solve.  What would a good title be for a scientific paper based on Burton’s question (Important!! – Review the section on titles on your handouts on Structuring Documents) and good luck in your own scientific brainstorming which could lead to worthwhile, exciting, glorious scientific work and papers.

21) Bottom p109 – Top 110.  Crichton states a problem and then provides Method and Methodology (p110-114).

        a) Restate the problem in the form of a title for a science paper and

        b) Provide four methods of the procedure

c) As you know, an ESSENTIAL trait of good scientific papers is that methods described can be REPEATED by other  scientists.  Could Crichton’s decontamination methods be REPEATED?  - Explain.

        d) Could Koop’s decontamination methods for meteorites be repeated exactly? (explain what Crichton includes AND deletes here. (p124)

        e) Why is the worldwide use of the black Norway rat so important for scientists’ REPEATING of experiments? (p 139-40)

22) p115.  Explain how Leavitt’s thinking about the history of a cure for cholera leads him to a hypothesis of “cure the symptoms, cure the disease.” (You must explain what the cure for cholera is and why it is effective.)

23) What is your opinion of Leavitt’s thinking about complex life (p115) and his conclusion about the possible size of life on other planets (p116)?  Is this logical, valid thinking?  Do you accept this hypothesis?  - Explain why/why not?

24) Draw a cartoon illustrating Chalmer’s example of microscopic extra terrestial life (p116). (Yes, stick figures are just fine.  You will not be assessed on drawing ability.  If you are talented in drawing, more power to you.  - I look forward to all your sketches.)

25) What are the similarities and differences between a bacterium on earth and Crichton’s fictional, extra-terrestrial bacteria? (p124)

26) How does Crichton explain the way a mutated bacterium could move back on earth? (p 27)

27) Why are the results of altered reproductive rate of bacteria in space and the fact that the results are ignored significant for this story? (Note the increased reproductive rate.)

28) When Leavitt postulates that debris in space might have caused a collision with the Scoop satellite, other scientists discount this as a far-fetched possibility.  How is Leavitt’s kind of imagination both “a strength and a defect” for scientists? (Bottom p137)

29) How can a pig be one of our best friends? (p 139)

For Extra Credit Bonus: Create a really good, subtle, witty, hearty joke about this pig-human connection.

30) What are growth media? (p 157) Name five.

31) Write out Burton’s experiment (top of p160) in the form of a Title, a 1 – 2 sentence Abstract, a 1 – 2 sentence Introduction (yes, provide Results).  Results (1 – 2 sentence) and Discussion (same length).

32) What are the results of Burton’s second experiment? (p161)

33) The evolutionary principle of biology whereby humankind and bacteria have adapted to one another results in increased reproductive potential for humans.  How? (bottom  p161)

34) What lessons could any scientist learn from Burton’s experimental technique (Name the experiment and explore steps in his experiment)?  Bottom 163–bottom 167.

35) Write up Burton’s experiment (p163-169) in the form of an Abstract, Introduction, Methods, Results, and Discussion.

36) Why do individuals addicted to methadol have shortness of breath as a symptom? Bottom 180.

37) Name the 2 substances the old man was treating himself with. (p 180)

38) Leavitt’s work on amino acids is an attempt to analyze the proteins of the foreign bacterium.  Name five of these essential acids. (Top p194)

 

 

RESOURCES

·       Chrichton, Michael : The Andromeda Strain

 

·       Websites:  See Below

 

·       Use these Public Policy websites to gather  information and write your work using the SIX STEP   Public Policy Analyst  Program:

 

Public Policy Analyst:

www.maxwell.syr.edu/plegal

 

Student educational resources:

www.maxwell.syr.edu/plegal/related.html

 

Tutorials on using computer technology:

www.maxwell.syr.edu/plegal/tips/tutorials.html

 

 

Websites for Bioterrorism  WebQuest

 

http://www.nytimes.com/2001/11/18/national/18pox.html?searchpv=past7days

http://www.state.in.us/isdh/healthinfo/bioterrorism.html

http://www.nytimes.com/aponline/technology/AP-anthrax-internet.html?searchpv=aponline

www.kitchendoctor.com/bioterrorism.html

www.terrorism.com/index.shtml

www.nbc-med.org/sitecontent/medref/onlineref/govdocs/biowarfare/index.html

http://www.fbi.gov/mostwant/terrorists/fugitives.html

http://www.cia.gov/cia/publications/cbr_handbook/cbrbook.html

http://abcnews.go.com/sections/living/dailynews/wtc_bioweapons.html

http://abcnews.go.com/sections/living/dailynews/terror_profiles_011010.fbk.html

http://www.bt.cdc.gov

http://www.apic.org/bioterror

http://www.csis.org/hill/ts01905cilluffo.html

http://www.terrorismfiles.com

http://www.terrorism.com/terrorism/groups2.html

http://www.bt.cdc.gov/

http://anthrax.com/nfws.htm

www.fda.gov/cber/cntrbio.htm

http://www.hhs.gov/hottopics/healing/biological.html

http://www.acponline.org/bioterro/

http://cns.miis.edu/pubs/reports/zilin.htm

http://www.nextstep.com/cgi-bin/article.cgi?file=/newmedianews/archive/2000/11/17/tsbioterrorism.dtl

http://www.washingtonpost.com/wp-dyn/nation/specials/attacked/A41225-2001Sep16.html

www.msnbc.com/news/635920.asp?cp1=1

http://nandotimes.com/dwb_data/v-include/?getstatic=/nt/topics/anthrax.html

http://www.newscientist.com/hottopics/bioterrorism/vitalmoments.jsp

http://www.survival-mindset.com/new_info.htm

www.stimson.org/cwc/terror.hlm

www.bt/cdc/gov/DocmentsApp/FactsAbout/FactsAbout.asp

http://www.cdc.gov/od/oc/media/qa.htm

http://www.fda.gov/cber/cntrbio/contribio.htm

http://www.hlm.nih.gov/medlineplus/news/fullstory_4785.html

http://www.cdc.gov/ncidod/eid/vol7no6/jernigan.htm

http://www.ama-assn.org/ama/pub/category/6667.html

http://www.avma.org/press/pibioterrorism01.asp

http://www/asm.org/pasrc/bioterrorismthreat.htm

http://www.stimson.org/cwc/terror.htm

http://www.nytimes.com/2001/11/18/national/18pox.html?searchpv=past7days

http://www.state.in.us/isdh/healthinfo/bioterrorism.html

http://www.nytimes.com/aponline/technology/AP-anthrax-internet.html?searchpv=aponline

www.kitchendoctor.com/bioterrorism.html

www.terrorism.com/index.shtml

www.nbc-med.org/sitecontent/medref/onlineref/govdocs/biowarfare/index.html

http://www.fbi.gov/mostwant/terrorists/fugitives.html

http://www.cia.gov/cia/publications/cbr_handbook/cbrbook.html

http://abcnews.go.com/sections/living/dailynews/wtc_bioweapons.html

http://abcnews.go.com/sections/living/dailynews/terror_profiles_011010.fbk.html

http://www.bt.cdc.gov

http://www.apic.org/bioterror

http://www.csis.org/hill/ts01905cilluffo.html

http://www.terrorismfiles.com

http://www.terrorism.com/terrorism/groups2.html

www.nytimes.com/reuters/bussiness/bussiness-economy.html?searchpv=reuters

www.nytimes.com/reuters/news/news-attack-anthrax.html?searchpv=reuters

http://news.bbc.co.uk/hi/english/sci/tech/newsid_1561000/1561360.stm

http://www.bio.psu.edu/people/faculty/whittam/research/bw.html

http://www.bt.cdc.gov/documentsapp/anthrax/11072001/clinician.asp

http://www.niaid.nih.gov/newsroom/releases/ebolavacc.html

http://www.nlm.nih.gov/medlineplus/news/fullstory_4505.html

http://proquest.umi.com/pqdweb?did=000000089490727&fmt=3&deli=1&mtd=1&idx=10&sid=2&rqt=309

www.bt.cdc.gov/documentsapp/factsabout/factsabout.asp

www.bioterrorism.com/

www.bt.cdc.gov/agent/smallpox/smallpoxconsensus.pdt

http://encarta.msn.com/find/concise.asp?z=1&pg=2&ti=761577286

www.bt.cdc.gov/agent/brucellosis/brucellosis.asp

www.galenet.com/servlet/litrc?c=4&stab=2048&ste=43&docnum=a63541477&ka=bioterrorism&bconts=2050&tab=2&vrsn=3&tbst=ksrch&srchtp=kywrd&n=10&locid=the35342

www.galenet.com/servlet/litrc?c=4&stab=2048&ste=43&docnum=a79409792&ka=bioterrorism&bconts=2050&tab=2&vrsn=3&tbst=ksrch&srchtp=kywrd&n=10&locid=the35342

http://www.galenet.com/servlet/src/hits?c=1&secondary=false&docnum=a80049718&sidebars=yes&bconts=60&bucket=4&origsearch=true&t=rk&s=1&r=d&n=10&items=0&1=dp&locid=the35342&su=bioterrorism

www.cdc.gov/health/disease.htm

www.bt.cdc.gov/agent/smallpox/smallpoxonsenus.pdf

www.hopkins-biodefense.org/pages/agents/agent.htm

http://www.galenet.com/servlet/src/hits?c=3&secondary=false&docnum=a80158024&sidebars=yes&bconts=60&bucket=4&origsearch=true&t=rk&s=1&r=d&n=10&items=0&1=dp&locid=the35342&su=bioterrorism

http://www.galenet.com/servlet/src/hits?c=3&secondary=false&docnum=a80158024&sidebqars=yes&bconts=60&bucket=4&origsearch=ture&t=rk&s=1&r=d&n=10&items=0&1=dp&locid=the35342&su=bioterrorism

http://www.galenet.com/servlet/src/hits?c=27&secondary=false&docnum=a79796036&sidebars=yes&bconts=60&bucket=4&origsearch=false&t=rk&s=1&R=d&n=10&items=0&1=dp&locid=the35342&su=bioterrorism

http://jama.ama-assn.org/issues/v286n20/ffull/jed10079.html

http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5010al.htm

http://www.cnn.com/2001/tech/internet/11/19/anthrax.internet.ap/index.html

www.dhfs.state.wi.us/dph-bcd/bioterrorism

http://www.niaid.nih.gov/publication/bioterrorism.htm

http://jama.ama-assn.org/issues/v286n20/ffull/jed10079.html

http://grants.nih.gov/grants/guides/rfa-files/rfa-a1-00.004.html

http://www.niaid.gov/factsheets/btrsch.htm

www.hopkins-biodefense.org/index/html

www.nlm.nih.gov/medlineplus/biologicalandchemicalweapons.html

www.bt.cdc.gov/documentsapp/factsabout.asp

www.hlm.nih.gov/medlineplus/news/fullstory_4566.html

www.medlineplus.nlm.gov/gov/medlineplus/news/fullstory_4517.html

www.medlineplus.nlm.gov/gov/medlineplus/news/fullstory_4406.html

http://www.fda.gov/oc/opacom/hottopics/bioterrorism.html

http://ohp.nasa.gov/alerts/anthrax.htm

http://www.cnn.com/2001/health/11/21/smallpox.treatment.ap/index.html

www.temujin.com

http://www.niaid.nih.gov/publications/bioterrorism.htm

www.pbs.org/wgbh/nova/bioterror/

www.news.bbc.co.uk/hi/english/sci/tech/newsid-1561000/1561360.slm

www.hhs.gov/hottopics/healing/biological.html

http://www.bt.cdc.gov/documentsapp/anthrax/11072001/clinician.asp

http://www.mayoclinic.com/invoke.cfm?id=mh00018

http://www.bt.cdc.gov/documentsapp/facts/about/factsabout.asp

 

EVALUATION

Your five page proposal or play, short story, or whatever format you have chosen, is the product you will hand in.  You will be judged on

 

a) how well you have educated your audience on the following:

                                               

-         The types and strains of micro – organisms likely to be deployed in biostrategy

-         How each  micro-organism attacks its human target

-         Testing and lab experimentation of pathogens

-         Known use of bio tactics against populations

-         Current status of production of pathogens in foreign countries

-         Techniques of dissemination of pathogens

-         Known antidotes and antibiotic measures successful against infection by planted pathogens

-         Availability of and positions for and against vaccine and vaccination techniques as preventative measures

-         How schools can create safe and feasible methods to protect its students.

 

Remember to include at least TWENTY facts or pieces of information from your research in your creative work. Highlight and number these in your work.

 

http://www.maxwell.syr.edu/plegal/tips/tutorials.html

 

b)  how you have creatively and imaginatively  used all the information gathered in your research to put together a work that will illustrate what we know about bioterrorism and how we can prevent  or react to a bioterrorist attack in the best way possible. 

 

c)      how thoroughly you have  looked up the Vocabulary words, writing one sentence for each of any twenty words .

Submit all definitions and the 25 sentences.

 

 

CONCLUSION

The written work you hand in will contain at least twenty  references to information found on the websites suggested or on other websites.  Your work must be able to be used by schools to distribute to children or to plan school policy.  Whether a creative piece or a policy proposal, the work should educate children about  biochemical micro-organisms and how individual children or their school can best react.  You could be instrumental in creating a  sane , intelligent and practical policy to a reality of the 21st Century.

 

“There is nothing to fear, but fear itself.”

Beat Bioterrorism by being Boldly, Bravely, Brilliantly Informed!