pharm animals: Are their products safe for us?

Is it ethical to use these animals to produce these products?

Carol Ravina

cravina@uticaschools.org

Ap Biology

Proctor High school, Utica NY

http://www.livinghistoryfarm.org/farminginthe70s/crops_12.html

http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/TransgenicAnimals.html

introduction:

Scientists are often accused of “playing God”, manipulating DNA in ways that are not natural. On the other hand, human population is increasing exponentially and there will not be enough resources to maintain human life on Earth. Bacteria have produced genetically human insulin to help diabetics or clotting factors for hemophiliacs. Transgenic bacteria don’t raise an alarm because they have been around and safe for years. But what about if the transgenic animal is a cow, goat or a cute cuddly rabbit?


	http://blog.myetutor.tv/higher-english-understanding-and-responding-to-the-higher-english-task

task:

You will complete several tutorials to increase your knowledge of genetic engineering and transgenic organisms. Then, your team will assess the risks and benefits in using transgenic organism in our food and drug supply and present the results as a PowerPoint to a group of elementary school parents.


	http://agung-theraider.blogspot.com/2012/03/procedure-text.html

process/procedure:

1. Complete the tutorial clone a mouse: http://learn.genetics.utah.edu/content/cloning/clickandclone/ . Take a screen shot of the final slide and attach it to your paperwork

2. Using the website: http://learn.genetics.utah.edu/content/science/pharming/ complete the creating a transgenic animal tutorial. Take a screen shot of the final slide and attach it to your paperwork

3. Complete the genetic engineering tutorial: http://agbiosafety.unl.edu/education/whowants.htm Take a screen shot of the final slide and attach it to your paperwork

4. Using the information from the PPA- Public Policy Analyst, you will follow the basic steps to research and present your problem. Steps:

http://www.cmtc.com/blog/bid/136843/Continuous-Improvement-DMAIC-Process-Control-and-Variation-Part-3

5. You will be divided into groups of 4 by me. I have given you two broad questions in the title. Using the worksheets from the PPA, select either one and refine it to a specific animal or drug product for your presentation.

a. Your PowerPoint must include at least 12 slides

b. Any images must link to the original website

c. Each person must present at least 3 slides.

d. You must discuss both pros and cons of the issue

e. Make sure your power point addresses the steps of the PPA


	http://et.engr.iupui.edu/sites/careerservices/studentsalumni/resources.php

resources:

· http://learn.genetics.utah.edu/content/science/pharming/

· http://www.technologyreview.com/view/411968/fda-approves-first-pharm-animals/

· http://www.livinghistoryfarm.org/farminginthe70s/crops_12.html

· http://www.cosmosmagazine.com/features/animal-pharm/

· http://vet.hcmuaf.edu.vn/data/file/application%20of%20biotechnology%20of%20animal%20health%20and%20production%20/Public%20perceptions%20of%20transgenic%20animals.pdf

· http://www.learner.org/interactives/dna/engineering.html

· http://www.actionbioscience.org/biotechnology/glenn.html

· http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078015/


	http://www.dreamstime.com/royalty-free-stock-photography-awesome- customer-evaluation-form-image26742737

evaluation:

Criteria	Excellent 4	Good 3	Average 2	Poor 1
Gathering Information: PPA	Problem is identified and researched thoroughly. All steps of the PPA are addressed and all the handouts are complete.	Problem is identified and researched. Most steps of the PPA are addressed. Most worksheets are completed correctly.	Problem is identified and partially researched. Some of the worksheets are incomplete.	Presentation does not follow PPA
Presentation: Information	All of the required topics are addressed in the PowerPoint, Content is accurate and ideas are supported well by research.	All of the required topics are addressed in the PowerPoint; some topics could have been researched more thoroughly. Content is accurate.	Not all sides of the issue are discussed Content is inaccurate.	Presentation strays from the topic. Content is inaccurate
Tutorials	Screen shots for all tutorials	Screen shots for 2 tutorials	Screen shots for 1 tutorial	No screen shots
Persuasive Argument: Grammar	Paper is grammatically correct. There are no spelling or punctuation mistakes.	There are one or two grammatical errors.	There are minor grammatical errors.	There are major grammatical errors
Group dynamics	All 4 students participated equally	Only 3 people participated equally; one did not	Only 2 people participated equally; two did not	Only one person did all the work

Total Possible Points: 20 Points Earned: ______

StandardS:

Cite specific textual evidence to support analysis of science and technical texts, attending to important distinctions the author makes and to any gaps or inconsistencies in the account
Determine the central ideas or conclusions of a text; summarize complex concepts, processes , or information presented in a text by paraphrasing them in simpler but still accurate terms
Follow precisely a complex multistep procedure when carrying out experiments, taking measurements, or performing technical tasks; analyze the specific results based on explanations in the text
Integrate and evaluate multiple sources of information presented in diverse formats and media (e.g., quantitative data, video, multimedia) in order to address a question or solve a problem.
Evaluate the hypotheses, data, analysis, and conclusions in a science or technical text verifying the data when possible and corroborating or challenging conclusions with other sources of information.
Synthesize information from a range of sources(e.g., texts, experiments, simulations) into a coherent understanding of a process, phenomenon, or concept, resolving conflicting information when possible


	http://www.dcielts.com/ielts-essays/conclusions-1/

Conclusion:

After completing this WebQuest, you should have a working knowledge of the general process of genetic engineering as it relates to cloning, genetic recombination and specifically to transgenic organisms as a food or drug source. You will have honed your critical thinking and presentation skills.